The key to maximizing your DPS as a Death Knight is through understanding what contributes most significantly to your DPS and what priorities you should follow when your circumstances deviate from the ideal. Whether it's a mobile encounter, or you miss an attack, or you need to refresh Horn of Winter, or your timing just gets off over the duration of a fight-- it will happen. Here's a suggested priority list for single target DPS
(1) Don't die.
(2) Keep your diseases (Blood Plague, Frost Fever) up 100% of the time. These boost your primary damage attacks significantly, and add a non-trivial amount to your dps themselves. Use a mod to track their remaining time.
(3) Use your highest damage-per-rune attack as much as possible, whenever it is available. Blood: Heart Strike, Frost 2h: Obliterate, Unholy: Scourge Strike.
(4) Spend your runic power before it hits the maximum. There's a common misconception that runic power is a secondary resource to runes. Your core RP abilities which include Death Coil, Frost Strike, Unholy Blight; all these do significant amounts of damage, and it's just as worthwhile to use an available global cooldown on one of these abilities as on a rune ability. Managing these can be tricky, especially in Blood spec when you have Sudden Doom procs to contend with also. Use the rune latency coding to your advantage-- there's an extra GCD in there after a rune becomes available (see: Rune Mechanics). When in doubt: as long as you are still not violating any of the previous three rules, dumping runic power will maximize your DPS.
(5) Use your spec's secondary strikes, talented appropriately, to convert off-spec runes into Death Runes. (Blood: Obliterate, Frost and Unholy: Blood Strike). This is in support of rule #3.
(6) Use your dps cooldowns appropriately to maximize their uptime. Know your rotations and how long the fight is, and judge accordingly. Note that cooldown use is an exception to rule #4: You'll want maximum runic power before using Gargoyle or Dancing Rune Weapon, for example.
(7) Do anything necessary to increase your raid's dps. While seeing big numbers fly by is fun, we have some abilities that may benefit the raid's overall damage more than a selfish buff to ourselves. Remember, the boss falling down is the ultimate goal. Use your discretion as to who in your raid might benefit most from Hysteria, a pure physical damage boost. Similarly, see the explanation of how Unholy Aura can benefit the raid significantly. If you're in charge of providing Abomination's Might (AP raid buff) or Imp. Icy Talons (haste raid buff), make sure they stay up.
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